To train students in essential concepts of genome dynamics and provide them with basic skills to use large scale genomic data for macroevolutionary reconstruction.

1. To understand, interpret and analyse models of genome evolution.
2. To understand phylostratigraphy principles and corresponding computational issues.
3. To apply evolutionary principles to the development of organs and the evolution of tumours.

1. Models of genome evolution – origin of the new genes and life cycle of genes.
2. Phylostratigraphy – basic principles of the approach and computational challenges.
3. Macroevolutionary analysis of transcriptomes and proteomes – expression data in macroevolutionary studies.
4. Evolution of multicellularity – molecular approaches.
5. Macroevolution of tumours – from the large-scale tumour data to the macroevolutionary origin of tumours.
6. Evolution of brain – how to trace evolutionary origin of our brains?
7. Evolution of molecular complexity – does evolution increases complexity?